Can you try the following:
Close all the Informatica clients. Go to start tab / button on windows machine
-> Select client tool which we would like to open -> right click -> more -> open file location
-> Select the client in location -> right click -> properties -> compatibility -> it will show option like "Change high DPI setting" save the setting if it will ask for save.
-> Repeast this step for all clients.
Restart the client machine and open the Informatica clients.